Peptide Science FOX04-DRI (Proxofim) is a synthetic peptide that belongs to a class of molecules known as senolytics. Senolytics are compounds that selectively target and eliminate senescent cells (cells that have stopped dividing and contribute to aging and age-related diseases). FOX04-DRI is designed to target and disrupt a specific protein complex, which is involved in maintaining the survival of senescent cells.
In particular, Proxofim (FOX04-DRI) targets the p53-dependent senescence pathway, which plays a key role in the growth arrest of senescent cells. By inhibiting this pathway, FOX04-DRI promotes the apoptosis (programmed cell death) of senescent cells, potentially reducing the harmful effects they have on tissue function, inflammation, and aging.
Key aspects of FOX04-DRI (Proxofim):